Dream Chemistry Lecture series


NaMeS students are invited to IPC PAS Seminar within DCL series delivered by:

Dr. Pawel Dydio

University of Strasbourg & CNRS, France

Mechanistic understanding, design, and multicatalysis in the development of catalytic reactions

Thursday, 20th May, 2021, 10 am, via Zoom 


link to join zoom seminar: zoom link

Meeting ID: 956 9808 8876

Passcode: 747976 


Chemical catalysis is key for sustainable development, by enabling cleaner technologies, improving the material- and energy-efficiency of chemical processes, and facilitating the valorization of renewable resources. Here I will discuss our research in the field of chemical catalysis driven by these motivations. Our research is pillared on three distinct but intertwined strategies, including the catalyst development by improving mechanistic understanding of the catalytic reactions, the development of new reactions by mechanistic design, and the development of (complex) transformations by relay multicatalysis. Each strategy will be portrayed with selected recent examples along with our current efforts.


[1] Martínez, S.; Veth, L.; Lainer, B.; Dydio, P. Challenges and Opportunities in Multicatalysis. ACS Catal. 2021, 3891–3915. https://doi.org/10.1021/acscatal.0c05725.

[2] Zhang, Y.; Torker, S.; Sigrist, M.; Bregović, N.; Dydio, P. Binuclear Pd(I)–Pd(I) Catalysis Assisted by Iodide Ligands for Selective Hydroformylation of Alkenes and Alkynes. J. Am. Chem. Soc. 2020, 142 (42), 18251–18265. https://doi.org/10.1021/jacs.0c09254.

[3] Casnati, A.; Lichosyt, D.; Lainer, B.; Veth, L.; Dydio, P. Multi-Catalytic Approach to One-Pot Stereoselective Synthesis of Secondary Benzylic Alcohols. Org. Lett 2021, asap https://doi.org/10.1021/acs.orglett.1c00939.

[4] Lichosyt, D.; Zhang, Y.; Hurej, K.; Dydio, P. Dual-Catalytic Transition Metal Systems for Functionalization of Unreactive Sites of Molecules. Nat. Catal. 2019, 2 (2), 114–122. https://doi.org/10.1038/s41929-018-0207-1.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 711859.